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Priogen

QuIC Kits

QuIC Kits

Regular price $250.00 USD
Regular price Sale price $250.00 USD
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Kits and Reagents
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The RT-QuIC Experts

Priogen's founding team operates one of the largest RT-QuIC labs in the world, running thousands of reactions every week. We are the only RT-QuIC kit supplier routinely testing both biological and ecological samples, with several experts ready to assist with the latest protocols. Our reagents are validated using positive and negative controls, ensuring high performance and quality.

Improve RT-QuIC performance with Nano-QuIC™

Priogen's Nano-QuIC™ technology improves RT-QuIC reaction kinetics and overcomes inhibitors associated with various sample types. By incorporating silica nanoparticles into the RT-QuIC assay, Nano-QuIC™ reduces detection times (top graph) and boosts sensitivity helping to reduce false-negative results (bottom graph). Read more about Nano-QuIC™ here.

  • Nano-QuIC™ Kit

    • Improves RT-QuIC reaction kinetics for the detection of prion disorders
    • Each kit provides reagents for one 96-well plate or 1/2 384-well plate
    • Ready to use, no filtering
    • Protocol available here
  • RT-QuIC Kit

    • Ultra-sensitive kit for detection of prion disorders
    • Each kit provides reagents for one 96-well plate or 1/2 384-well plate
    • Ready to use, no filtering
    • Protocol available here
  • 10X Sample Dilution Buffer

    • For use with Nano-QuIC™ and RT-QuIC kits
    • 1% SDS, 10X PBS (1.1 mL)
    • Ready to use, no filtering
    • Protocol available here

PrioPriotein™ QuIC Substrate

Priogen's QuIC kits ship with PrioProtein™, a Syrian hamster recombinant truncated prion protein (amino acids 90–231) optimized for QuIC experiments. Concentration determined with A280, mass attenuation coefficient of 1.4, purified with nickel-affinity chromatography. Every batch of PrioProtein™ is produced with high quality control through current Good Manufacturing Practice aligning with FDA CFR Title 21 Part 211, and is internally validated for performance before shipping as part of RT-QuIC and Nano-QuIC™ kits.