Tricision

Unparalleled CWD Live-Animal Testing Accuracy

Tricision™ provides revolutionary CWD management through triangulation-based RT-QuIC testing of three sample types. Accounting for different stages of CWD, Tricision™ is the most accurate live test available. Perfect for deer and elk producers, rehabilitation centers, and zoos.

For more information, please email sales@priogen.bio or call 612-200-2643 ext 2.

  • Oral Swab

    CWD prions are shed into the saliva of infected animals within months of infection. An oral swab followed by RT-QuIC testing can identify early, mid, and late stage CWD infections.

  • Ear Punch

    Several studies have recently shown that RT-QuIC testing of ear punches is an effective way to identify CWD. This tissue type is likely most effective during mid to late stages of the disease.

  • Feces

    The shedding of CWD prions into the feces of infected animals can begin within months of an infection and remain throughout mid and late stages. RT-QuIC has been shown to be effective at identifying CWD prions in feces.

What makes Tricision™ superior to other methods?

  • Unlike traditional methods, all Tricision™ samples are secured using disposable tools, thus eliminating risk of introducing CWD to new animals and herds through contaminated surgical tools. 

  • Conventional live-animal testing using rectal biopsies is ~75-80% accurate and has a high false-negative rate due to inability to detect early-stage infections. Priogen's proprietary diagnostic testing protocols using QuIC technologies provide unparalleled CWD diagnostic accuracy at 91% to 100%.

  • Tricision™ is minimally invasive and repeatable testing allows for early detection.

Results from tissues directly from animals indicating a CWD-positive or suspect animal will be reported to the appropriate State/Provincial/Federal agencies as required by law. (Note: please follow all state, provincial, and federal regulations for mandatory testing.)

The Science Behind Tricision

CWD spreads at different rates within infected deer or elk and CWD prions appear in fluids and tissues at different times. For this reason, a multi-sample approach is the best way to identify CWD positive animals during early, mid, and late stages of disease. Traditional methods focused on one tissue type do not account for disease timecourse.

Genetic background is also important when testing for CWD. Some deer or elk are more susceptible, with CWD prions spreading readily through their body, making them easier to detect. Other animals are less suceptible, they still get CWD but prions replicate less efficiently, and they are more difficult to detect. Because Tricision™ uses 3 samples, the diagnostic sensitivity is increased, helping to account for variable prion shedding in a given animal.

For more information on our services, please call 612-200-2643 ext 2.