Live Animal Testing

Priogen's Tricision™ CWD test is the most accurate and minimally invasive live-animal test available

The Future is Now

Tricision™ provides revolutionary CWD management through triangulation-based RT-QuIC testing of three sample types. Accounting for different stages of CWD, Tricision™ is the most accurate live test available. Perfect for state and tribal agencies, deer and elk producers, rehabilitation centers, and zoos.

Results indicating a CWD-positive or suspect animal will be reported to the appropriate State/Provincial/Federal agencies as required by law. (Note: please follow all state, provincial, and federal regulations for mandatory testing.)

For more information and a customized quote, please email sales@priogen.bio or call 612-200-2643 ext 2.

Maximize diagnostic sensitivity and specificity through triangulation testing:

Oral Swab

CWD prions are shed into the saliva of infected animals within months of infection. An oral swab followed by RT-QuIC testing can identify early, mid, and late stage CWD infections.

Ear Punch

Several studies have recently shown that RT-QuIC testing of ear punches is an effective way to identify CWD. This tissue type is likely most effective during mid to late stages of the disease.

Feces

The shedding of CWD prions into the feces of infected animals can begin within months of an infection and remain throughout mid and late stages. RT-QuIC has been shown to be effective at identifying CWD prions in feces.

Tricision™: Precision Testing for CWD — Safe, Accurate, and Minimally Invasive

Disposable Tools

Unlike rectal biopsies, all Tricision™ samples are secured using disposable tools, thus eliminating risk of introducing CWD to new animals and herds through contaminated surgical tools.

Overcoming RNA Limitations

Methods focusing on RNAs or micro-RNAs present in blood typically require specialized preservation methods and time consuming gene expression analyses. These targets can be influenced by a variety of factors including stage of disease, animal stress, age, and co-infections with other ailments. Priogen targets the causative agent of CWD (prions) to confirm the presence of the disease.

Accuracy

Rectal biopsies are only ~75-80% accurate and have a high false-negative rate due to limited detection of early-stage CWD infections. Priogen's proprietary diagnostic testing protocols using QuIC technologies provide unparalleled CWD diagnostic accuracy at 91% to 100%.

Repeatable

Tricision™ offers minimally invasive procedures that are easily repeated. The triangulation approach enables early detection and confirmation can easily be secured through repeat testing.

The Science of CWD Live-Animal Testing

CWD spreads at different rates within infected deer or elk and CWD. For this reason, a multi-sample approach is the best way to identify CWD positive animals during early, mid, and late stages of disease. Traditional methods focused on one sample type do not account for disease time-course. Because Tricision™ uses 3 samples, the diagnostic sensitivity is increased, helping to account for variable prion shedding in a given animal.

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